Mechanism of Hydrogen-Bonded Complex Formation between Ibuprofen and Nanocrystalline Hydroxyapatite
- Submitting institution
-
The University of Bradford
- Unit of assessment
- 12 - Engineering
- Output identifier
- 31
- Type
- D - Journal article
- DOI
-
10.1021/acs.langmuir.6b04510
- Title of journal
- Langmuir
- Article number
- -
- First page
- 2965
- Volume
- 33
- Issue
- 12
- ISSN
- 0743-7463
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2017
- URL
-
https://pubs.acs.org/doi/10.1021/acs.langmuir.6b04510
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
7
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Hydroxyapatite can be combined with drugs such as anti-inflammatories to offer great benefits for fracture fixation and osseointegration of implants. This study provides a detailed basis from which to develop these products. The study is a collaboration between engineering and pharmacy research groups at Bradford University, with chemistry and dentistry groups at Sheffield University, combining many different areas of expertise. The work built on a multi-institutional EPSRC/MRC grant (MR/K027158/1, funding value £198354) and is the basis for ongoing collaboration in biomaterials research. Ceramisys Ltd. are commercialising work related to this study for clinical application in bone repair.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
