An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells
- Submitting institution
-
The University of Surrey
- Unit of assessment
- 12 - Engineering
- Output identifier
- 9004870_2
- Type
- D - Journal article
- DOI
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10.1038/nnano.2015.19
- Title of journal
- Nature Nanotechnology
- Article number
- -
- First page
- 361-369
- Volume
- 10
- Issue
- 4
- ISSN
- 1748-3387
- Open access status
- Out of scope for open access requirements
- Month of publication
- -
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
-
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The role of calcium phosphate nanoparticles formed in the gut is controversial and was previously thought to be a minor pathway for the excretion of Ca. Ion beam analysis at Surrey was used to confirm the chemical composition of the particles. This work provides important new insights into the interplay between nutrition, gut physiology and the mucosal immune system and even indicates that mineralised Ca nanoparticles in breast milk may facilitate early gut immuno-surveillance of maternal milk-borne antigens.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -