Determination of work of adhesion of biological cell under AFM bead indentation
- Submitting institution
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The University of Warwick
- Unit of assessment
- 12 - Engineering
- Output identifier
- 8217
- Type
- D - Journal article
- DOI
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10.1016/j.jmbbm.2015.11.034
- Title of journal
- Journal of the Mechanical Behavior of Biomedical Materials
- Article number
- -
- First page
- 77
- Volume
- 56
- Issue
- -
- ISSN
- 1751-6161
- Open access status
- Out of scope for open access requirements
- Month of publication
- March
- Year of publication
- 2016
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This research described Atomic Force Microscope (AFM) measurements and modelling of the mechanical properties (such as elastic modulus) of biological cells. The approach is of potential use in the diagnosis of diseased cells. The work led to two EU grants on applications: FP7-MSCA-IRSES Biomedical Robotics and Applications (BioRA, €446k, 2013-2017); and H2020-RISES MNR4Cell (€1.2m, 2017-2020) to explore the manipulation of single cancer cells, with a consortium of 10 partners. This article was a major contributor to the first-author's appointment to a faculty position of Associate Professor in Tianjin University of China in 2018.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -