Analysis of protein coatings on gold nanoparticles by XPS and liquid-based particle sizing techniques
- Submitting institution
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The University of Surrey
- Unit of assessment
- 12 - Engineering
- Output identifier
- 9027841_1
- Type
- D - Journal article
- DOI
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10.1116/1.4913566
- Title of journal
- Biointerphases
- Article number
- -
- First page
- 019012
- Volume
- 10
- Issue
- 1
- ISSN
- 1934-8630
- Open access status
- Out of scope for open access requirements
- Month of publication
- -
- Year of publication
- 2015
- URL
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- Supplementary information
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- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
-
- Research group(s)
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- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This manuscript demonstrates consistency in the measurement of number of biomolecules at the surface of nanoparticles when measured using liquid-based sizing methods compared to XPS in vacuum. This validation is of importance since many nanoparticles are suitable for characterisation by only one of the two methods. This work directly led to a successful international VAMAS interlaboratory study ‘Measurement of surface chemistry & thickness of nanoparticle coatings’ and was used as input to the development of an ISO standard on surface chemical analysis (ISO 20579-4:2018). These methods have since been applied to the analysis of many industrial samples at NPL.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -