Analysis of parasitic protozoa at the single-cell level using microfluidic impedance cytometry
- Submitting institution
-
University of Southampton
- Unit of assessment
- 12 - Engineering
- Output identifier
- 34065455
- Type
- D - Journal article
- DOI
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10.1038/s41598-017-02715-y
- Title of journal
- Scientific Reports
- Article number
- 2601
- First page
- 1
- Volume
- 7
- Issue
- 1
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- June
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This work was performed in collaboration with Scottish Water, who currently use a labour intensive microscopy based process to monitor drinking water for the presence of pathogens (EP1623.1). This paper demonstrates a rapid electrical based method that could be used as an automated continuous monitoring platform. Importantly, the work demonstrated discrimination of live from dead pathogens - not possible using current methods. The method reduces the incidence of false-positive events where dead cells are detected as pathogenic, triggering enhanced sterilisation procedures which is very costly. The work led to an invited talk (http://www.ibca2018.net/speakers.html).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -