Early vascular damage from smoking and alcohol in teenage years : the ALSPAC study
- Submitting institution
-
King's College London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 105152511
- Type
- D - Journal article
- DOI
-
10.1093/eurheartj/ehy524
- Title of journal
- European Heart Journal
- Article number
- -
- First page
- 345
- Volume
- 40
- Issue
- 4
- ISSN
- 0195-668X
- Open access status
- Compliant
- Month of publication
- August
- Year of publication
- 2018
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 1 - Clinical Medicine
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
9
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This study demonstrates for the first time that smoking and alcohol in adolescence are associated with increased aortic stiffening as measured by established pressure waveform analysis. In addition, smoking cessation can reverse these arterial changes. Considering that aortic stiffness increases the risk for premature heart disease, the findings of this paper provide important public health messages. This information attracted media coverage with interviews in newspapers (Daily Telegraph, Guardian, Times), BBC radio news, https://www.ucl.ac.uk/news/headlines/2018/aug/teenagers-who-smoke-or-binge-drink-have-stiffer-arteries. BHF funding (CS/15/6/31468) to further assess cardiovascular changes in adulthood in the same cohort has been secured.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -