Intracellularly Biodegradable Polyelectrolyte/Silica Composite Microcapsules as Carriers for Small Molecules
- Submitting institution
-
Queen Mary University of London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 580
- Type
- D - Journal article
- DOI
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10.1021/acsami.6b01921
- Title of journal
- ACS Applied Materials and Interfaces
- Article number
- -
- First page
- 9651
- Volume
- 8
- Issue
- 15
- ISSN
- 1944-8252
- Open access status
- Out of scope for open access requirements
- Month of publication
- April
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The fabrication of composite shell for polymer-based capsules led to unique multimodal properties. The novelty is in situ fabrication of SiO2 nanostructures within polyelectrolyte layers of the microcapsule wall. The capsules became non-permeable for low molecular weight molecules, extremely sensitive to ultrasound and fully degradable inside biological cells. Combining these properties can engineer delivery systems able to carry small bio-active molecules inside biological cells not achieved by other methods. Gao defended her thesis and was appointed Ass.Professor in Beihang University, Beijing, China and Tarakina became Electron Microscopy Group Leader at Max Plank Institute of Colloids and Interfaces [www.mpikg.mpg.de/staff-members/59609].
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
