Adding functionality with additive manufacturing : fabrication of titanium-based antibiotic eluting implants
- Submitting institution
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The University of Birmingham
- Unit of assessment
- 12 - Engineering
- Output identifier
- 31184442
- Type
- D - Journal article
- DOI
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10.1016/j.msec.2016.04.006
- Title of journal
- Materials Science and Engineering C
- Article number
- -
- First page
- 407
- Volume
- 64
- Issue
- -
- ISSN
- 0928-4931
- Open access status
- Compliant
- Month of publication
- April
- Year of publication
- 2016
- URL
-
-
- Supplementary information
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- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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8
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Overuse of antibiotics significantly contributes to the global threat of antimicrobial resistance. In this paper we exploit additive manufacturing to produce implant designs that may be loaded with antibiotic eluting materials. By enabling local release of the drug, the overall dosage can be reduced compared with systemic administration. This work led to further funding (EPSRC, £817,124, EP/P02341X/1) and new industrial collaborations with Accentus Medical (contact: Philip Agg, philip.agg@accentus-medical.com) and Renishaw PLC (contact: Bryan Austin, Bryan.Austin@Renishaw.com). The paper has also been cited by an international leader in additive manufacturing, Professor Bose (Washington State University), and led to a further publication (https://doi.org/10.1016/j.addma.2018.01.005).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -