Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation
- Submitting institution
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University of Portsmouth
- Unit of assessment
- 12 - Engineering
- Output identifier
- 7138114
- Type
- D - Journal article
- DOI
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10.1016/j.jmbbm.2014.06.015
- Title of journal
- Journal of the Mechanical Behavior of Biomedical Materials
- Article number
- -
- First page
- 9
- Volume
- 39
- Issue
- -
- ISSN
- 1751-6161
- Open access status
- Out of scope for open access requirements
- Month of publication
- July
- Year of publication
- 2014
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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7
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The current study (supported by Medical Research Council 23369 (G0900453), EPSRC (EP/P503841/1) and the AAIR Charity) of nanomechanics of human tissue showed an innovative application of AFM cantilever-based nanoindentation. The paper is significant because it established reliable experimental protocol and data analysis that were quantitatively validated with results obtained from conventional and AFM methods on materials with known properties. Suggested protocol, boundaries and findings in this paper acted as guidelines in international studies on osteoarthritis (Olive et al., Comput Methods Biomech Biomed Engin 2017), bone (Wingender et al. Materials 2018), and most recently fibrils (Magerle et al, Anal Chem 2020).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -