Investigation of Within-Tablet Dynamics for Extended Release of a Poorly Soluble Basic Drug from Hydrophilic Matrix Tablets Using ATR-FTIR Imaging
- Submitting institution
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Sheffield Hallam University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 3890
- Type
- D - Journal article
- DOI
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10.1021/acs.molpharmaceut.9b01063
- Title of journal
- Molecular Pharmaceutics
- Article number
- -
- First page
- 1090
- Volume
- 17
- Issue
- 4
- ISSN
- 1543-8384
- Open access status
- Other exception
- Month of publication
- February
- Year of publication
- 2020
- URL
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- Supplementary information
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- Request cross-referral to
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- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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4
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper was funded by Sheffield Hallam University and was a collaboration between Bristol-Myers Squibb, University of Huddersfield and SHU imaging the mobility and release kinetics of poorly soluble pharmaceutical active ingredients as a function of pH. The paper won the Royal Society of Chemistry Duncan Bryant Award 2020 which is given for the most outstanding paper by an early career researcher within UK industry or academia, in any field of molecular spectroscopy applied to pharmaceutical science.
- Author contribution statement
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- Non-English
- No
- English abstract
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