Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system
- Submitting institution
-
University of Hertfordshire
- Unit of assessment
- 12 - Engineering
- Output identifier
- 13466300
- Type
- D - Journal article
- DOI
-
10.1038/s41598-017-11533-1
- Title of journal
- Scientific Reports
- Article number
- 12045
- First page
- -
- Volume
- 7
- Issue
- -
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 5 - Biological Sciences
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Nanoformulations significantly increase the uptake of active compounds, enhance the efficacy of drugs, and can be functionalised to target specific tissues, e.g. solid tumours. Ingenious engineering in combination with microfluidics allows control over the processing conditions, as shown in this article. The work was a close collaboration between the University of Strathclyde and UCL which lead to follow-up applications for funding and state of the art technology development with strong potential for commercialisation. A funded studentship at the University of Hertfordshire continues this work with the lead Author. This research is driving the pharmaceutical manufacturing of to-scale, on-demand medicine formulations
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -