In-vitro antibacterial and anti-encrustation performance of silver-polytetrafluoroethylene nanocomposite coated urinary catheters
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 48541781
- Type
- D - Journal article
- DOI
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10.1016/j.jhin.2019.02.012
- Title of journal
- Journal of Hospital Infection
- Article number
- -
- First page
- 55
- Volume
- 103
- Issue
- 1
- ISSN
- 0195-6701
- Open access status
- Compliant
- Month of publication
- February
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
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7
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections, leading to increased morbidity and mortality. We developed a new nanocomposite coating for catheters, which extended the time to develop bacteriuria from 6 days to 41 days and the time to develop encrustation from 35 days to 91 days. The coated catheters demonstrated excellent biocompatibility with fibroblast cells in culture, making it a prospective strategy to overcome current challenges in CAUTIs. The clinical trials for the coated urinary catheters are performed in the collaborations with medical device manufacturers and hospitals. This research was supported by EPSRC through EP/P00301X/1.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -