A naturally protective epitope of limited variability as an influenza vaccine target
- Submitting institution
-
The University of Kent
(joint submission with University of Greenwich)
- Unit of assessment
- 3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
- Output identifier
- 14152
- Type
- D - Journal article
- DOI
-
10.1038/s41467-018-06228-8
- Title of journal
- Nature communications
- Article number
- 3859
- First page
- -
- Volume
- 9
- Issue
- 1
- ISSN
- 2041-1723
- Open access status
- Compliant
- Month of publication
- September
- Year of publication
- 2018
- URL
-
https://kar.kent.ac.uk/69235/
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
15
- Research group(s)
-
B - Biological Sciences
- Citation count
- 16
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- -
- Author contribution statement
- Dr Temperton’s contribution:
As assay: The Temperton pseudoptyed virus assay enabled panels of H1N1 serological assays (historical strains) to be assembled and implemented at scale for the detailed analysis of immune responses in sera from young children.
As immunogen: Pseudotyped viruses produced by Temperton were used as the basis of animal model vaccination studies to assess the validity of the vaccine targeidentified by bioinformatics pipeline.
- Non-English
- No
- English abstract
- -
