Apatite formation of bioactive glasses is enhanced by low additions of fluoride but delayed in the presence of serum proteins
- Submitting institution
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Queen Mary University of London
- Unit of assessment
- 12 - Engineering
- Output identifier
- 692
- Type
- D - Journal article
- DOI
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10.1016/j.matlet.2015.04.013
- Title of journal
- Materials Letters
- Article number
- -
- First page
- 143
- Volume
- 153
- Issue
- -
- ISSN
- 0167-577X
- Open access status
- Out of scope for open access requirements
- Month of publication
- August
- Year of publication
- 2015
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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3
- Research group(s)
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-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Demonstrated that at neutral pH, fluorine incorporation and dose control in bioactive glass is key to formation of single phase apatite. The presence of proteins delayed (but did not arrest) apatite formation, indicating the approach was exploitable to drive enamel remineralisation in the oral environment. Results key to development and clinical translation and development of BioMinF™ toothpaste to treat dentine hypersensitivity, sold in over 20 countries worldwide https://biomin.co.uk/products/biominr-f-toothpaste. BioMinF™ featured in the ‘How to make’ BBC4 documentary series aired 9 April 2020. Clinical trials confirmed efficacy and that BioMinF™ reduces dentine hypersensitivity more effectively than conventional ‘sensitivity’ toothpastes. https://biomin.co.uk/news/article/italian-study-shows-biomin-f-works-against-sensitivity https://DOI.org/10.1111/joor.12847
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
