Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling
- Submitting institution
-
Abertay University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 17661777
- Type
- D - Journal article
- DOI
-
10.3389/fimmu.2018.00637
- Title of journal
- Frontiers in Immunology
- Article number
- 637
- First page
- -
- Volume
- 9
- Issue
- -
- ISSN
- 1664-3224
- Open access status
- Compliant
- Month of publication
- March
- Year of publication
- 2018
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
8
- Research group(s)
-
D - Modelling & Simulation
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- In this 2018 paper, we use an agent-based model of the network of blood vessels in the liver to test a hypothesis about inflammation, and confirm the model's predictions using a conventional in-vivo experiment. The paper has been cited in papers making use of the inflammation finding, and is noted as one of several "examples of exciting progress" in a 2019 WIREs Mechanisms of Disease review of agent-based models of inflammation.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
