Annulus fibrosus functional extrafibrillar and fibrous mechanical behaviour: experimental and computational characterisation
- Submitting institution
-
The University of Leeds
- Unit of assessment
- 12 - Engineering
- Output identifier
- MECH-72
- Type
- D - Journal article
- DOI
-
10.1098/rsos.170807
- Title of journal
- Royal Society Open Science
- Article number
- 170807
- First page
- -
- Volume
- 4
- Issue
- 8
- ISSN
- 2054-5703
- Open access status
- Compliant
- Month of publication
- August
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- International collaboration with Wilfried Laurier University, funded through EPSRC and ERC grants (EP/K020757/1, EP/F010575/1, 2012-StG-306615), resulted in this new approach for experimental characterisation of soft tissues coupled with state-of-the-art specimen-specific computational modelling methods. Supported by first multi-specimen direct validation, this paper offers clear recommendations on complexity required in intervertebral disc modelling and physical testing. This new framework provides confidence that the methodology captures measurable population variation. The approach developed in this paper has been adapted to other tissues and degenerated spines, forming the basis of follow-on work on knee and spinal interventions, funded by EPSRC programme EP/P001076/1.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
