CD28null pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of Cardiovascular death
- Submitting institution
-
University of Sussex
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 115097_77823
- Type
- D - Journal article
- DOI
-
10.7150/thno.27428
- Title of journal
- Theranostics
- Article number
- -
- First page
- 4509
- Volume
- 8
- Issue
- 16
- ISSN
- 1838-7640
- Open access status
- Compliant
- Month of publication
- August
- Year of publication
- 2018
- URL
-
https://doi.org/10.7150/thno.27428
- Supplementary information
-
-
- Request cross-referral to
- 1 - Clinical Medicine
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
14
- Research group(s)
-
-
- Citation count
- 14
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- FightAging.org mentions the paper in its blog (15/08/2018) commenting: "Researchers here point to one specific consequence of the accumulation of a problematic class of T cell noted to occur with aging, increased risk of cardiovascular disease, and present evidence to show that this accumulation occurs because of persistent CMV infection. All told, the evidence for?CMV to be a major issue, a slow corrosion of immune function and health, is quite compelling." Indeed, strategies targeting these cells in patients at risk of coronary complications should consider the use of specific anti-viral drugs. Field-weighted citation impact 1.84 (Scopus).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -