Use of lanthanide-containing polyoxometalates to sensitise the emission of fluorescent labelled serum albumin
- Submitting institution
-
Glasgow Caledonian University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 33269782
- Type
- D - Journal article
- DOI
-
10.1002/cphc.201500954
- Title of journal
- ChemPhysChem : a European Journal of Chemical Physics and Physical Chemistry
- Article number
- -
- First page
- 418
- Volume
- 17
- Issue
- 3
- ISSN
- 1439-4235
- Open access status
- Out of scope for open access requirements
- Month of publication
- December
- Year of publication
- 2015
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The originality of this paper lies in using polyoxometalates (POM), which are a novel class of non-toxic biocompatible molecules that exhibit long lived luminescence. This property has been exploited here to demonstrate a sensor for proteins using an innovative luminescence approach. The paper rigorously explores the proposed sensor for two lanthanide centred POM molecules, where the Eu-POM based sensor demonstrated an efficiency of >90% for the detection of labelled serum albumin. There is an in-depth analysis of the results obtained with complex issues highlighted. This is critical information for the future development of biosensors based on these complexes.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -