Silk fibroin/gelatin microcarriers as scaffolds for bone tissue engineering
- Submitting institution
-
University of Plymouth
- Unit of assessment
- 12 - Engineering
- Output identifier
- 1813
- Type
- D - Journal article
- DOI
-
10.1016/j.msec.2019.110116
- Title of journal
- Materials Science and Engineering: C
- Article number
- 110116
- First page
- -
- Volume
- 106
- Issue
- -
- ISSN
- 0928-4931
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
2
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This paper is an important example of how interdisciplinary collaborations between materials scientists, stem cell biologists and biochemical engineers can contribute to tissue engineering. It describes how the combination of silk fibroin and gelatin can be used to create three-dimensional microcarriers for the dynamic culture of mesenchymal stem cells to support their differentiation along an osteogenic pathway. The importance of this work is that it shows, for the first time, that the presence of gelatin significantly enhances the mechanical properties of silk fibroin.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -