Multilayered composite coatings of titanium dioxide nanotubes decorated with zinc oxide and hydroxyapatite nanoparticles: Controlled release of Zn and antimicrobial properties against staphylococcus aureus
- Submitting institution
-
University of Plymouth
- Unit of assessment
- 12 - Engineering
- Output identifier
- 1758
- Type
- D - Journal article
- DOI
-
10.2147/IJN.S199219
- Title of journal
- International Journal of Nanomedicine
- Article number
- -
- First page
- 3583
- Volume
- 14
- Issue
- -
- ISSN
- 1176-9114
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2019
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
4
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- There is no single material currently used in orthopaedic or dental implants combining the mechanical properties, biocompatibility and antimicrobial activity required for a successful implant. This paper describes the successful development of a new medical grade Ti-6Al-4V alloy, whose surface was modified by growing TiO2 nanotubes, decorated with an antimicrobial layer of zinc oxide nanoparticles, and adding a biocompatible layer of hydroxyapatite crystals. The significance of this output is that it demonstrates that the multi-layered composite coatings are not only stable but have strong antimicrobial properties and, as a consequence, offer an alternative strategy for infection control in medical implants.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -