A phenomenological model of myelinated nerve with a dynamic threshold
- Submitting institution
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The University of Warwick
- Unit of assessment
- 12 - Engineering
- Output identifier
- 8601
- Type
- D - Journal article
- DOI
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10.1016/j.jtbi.2015.06.035
- Title of journal
- Journal of Theoretical Biology
- Article number
- -
- First page
- 386
- Volume
- 382
- Issue
- -
- ISSN
- 0022-5193
- Open access status
- Out of scope for open access requirements
- Month of publication
- October
- Year of publication
- 2015
- URL
-
-
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
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2
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The first phenomenological mathematical model to accurately reproduce the response to electrical stimulation of the first layer of coding neurons in the auditory system. The model supports ongoing research to improve the performance of cochlear implants, in partnership with Advanced Bionics, Guy's and St Thomas' Hospital Trust, and the House Ear Institute (California). Computationally efficient and validated by physiological experiments, the model opens up the possibility of simulating extremely large populations of neurons. The methodology underpinned and enabled EPSRC grants EP/H000682/1, EP/C523334/1 and EP/D051894/1 to develop novel cochlear implant coding strategies (total value: £880k).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -