Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy
- Submitting institution
-
University of Keele
- Unit of assessment
- 12 - Engineering
- Output identifier
- 408
- Type
- D - Journal article
- DOI
-
10.1038/s41598-018-20287-3
- Title of journal
- Scientific Reports
- Article number
- 1898
- First page
- -
- Volume
- 8
- Issue
- 1
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- January
- Year of publication
- 2018
- URL
-
https://www.nature.com/articles/s41598-018-20287-3?source=techstories.org
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
10
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- A study describing, for the first time, that muscle retains a genetic memory of ‘bulking up’ after a return to normal levels. Originally funded with support from GlaxoSmithKline and Keele University the study, published in Scientific Reports, was ranked as 6th most impactful of all in 2018, and as a result benefitted from tailored, journal produced, YouTube video content and a Nature author interview. The study itself underpinned a successful PhD completion for Dr Seaborne (now PDRA at QMUL Blizzard Institute) and recruitment of Dr Sharples to initiate and lead a unit at the Norwegian School of Sports Sciences, Oslo.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -