Second harmonic generation (SHG) imaging of cancer heterogeneity in ultrasound guided biopsies of prostate in men suspected with prostate cancer
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 28150987
- Type
- D - Journal article
- DOI
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10.1002/jbio.201600090
- Title of journal
- Journal of Biophotonics
- Article number
- -
- First page
- 911
- Volume
- 10
- Issue
- 6-7
- ISSN
- 1864-063X
- Open access status
- Compliant
- Month of publication
- August
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
8
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Extracellular matrix remains an important component of tumour micro-environment and influences growth of cancers. Second harmonic generation (SHG) imaging provides high‐resolution images of collagen distribution in prostate to characterise this component and provide risk stratification for cancers. The method provided a clear diagnostic accuracy between cancer and benign tissues and could differentiate between grades of cancer. Media highlight through Advance Science News on 15th September 2017. This paper also demonstrates our multidisciplinary multimodality imaging research in enhancing early cancer diagnosis.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
