Deformability-induced lift force in spiral microchannels for cell separation
- Submitting institution
-
University of Glasgow
- Unit of assessment
- 12 - Engineering
- Output identifier
- 12-09248
- Type
- D - Journal article
- DOI
-
10.1039/C9LC01000A
- Title of journal
- Lab on a Chip
- Article number
- -
- First page
- 614
- Volume
- 20
- Issue
- -
- ISSN
- 1473-0197
- Open access status
- Compliant
- Month of publication
- -
- Year of publication
- 2020
- URL
-
http://eprints.gla.ac.uk/207709/
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The technique enables the high throughput microfluidic-based separation of cells based on their mechanical properties, and led to a 3-year EPSRC Post-Doctoral Fellowship (EP/R006482, https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/R006482/1, £357,335) and a 5-year Royal Academy of Engineering Research Fellowship (RF\201718\1741). The work was translated clinically in the NHS through a Chief Scientist Office Translation Grant (TCS/19/46, https://www.cso.scot.nhs.uk/outputs/cso-funded-research/tcs2019/, £295,085) in collaboration with Drs Peveler , Murphy, Baillie and Prof. Goodyear for application in hospitals to separate pathogens causing blood stream infections. The technology also highlighted the role of engineering in the fight against antimicrobial resistance (The Engineer Magazine, December 2019, shorturl.at/joyQZ).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
