Oxygen-enhanced and dynamic contrast- enhanced optoacoustic tomography provide surrogate biomarkers of tumor vascular function, hypoxia, and necrosis
- Submitting institution
-
University of Dundee
- Unit of assessment
- 12 - Engineering
- Output identifier
- 54354522
- Type
- D - Journal article
- DOI
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10.1158/0008-5472.CAN-18-1033
- Title of journal
- Cancer Research
- Article number
- -
- First page
- 5980
- Volume
- 78
- Issue
- 20
- ISSN
- 0008-5472
- Open access status
- Technical exception
- Month of publication
- August
- Year of publication
- 2018
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The manuscript reports a novel method to probe tumor micro-environment using photoacoustic imaging. In this manuscript, we showed that oxygen-enhanced and dynamic contrast-enhanced photoacoustic imaging can be used to profile vascular function, hypoxia and tumour necrosis. It is expected that this approach will be easily translated into clinical photoacoustic imaging applications for profiling tumor vascular function and hypoxia as evidenced by the following publications: DOI: 10.1158/0008-5472.CAN-18-3769, DOI: 10.1158/0008-5472.CAN-19-3247, DOI: 10.1016/j.neo.2020.11.006, DOI: 10.1158/0008-5472.CAN-19-3247
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -