An injectable scaffold based on crosslinked hyaluronic acid gel for tissue regeneration
- Submitting institution
-
The University of Birmingham
- Unit of assessment
- 12 - Engineering
- Output identifier
- 30648423
- Type
- D - Journal article
- DOI
-
10.1039/c5ra27870h
- Title of journal
- RSC Advances
- Article number
- -
- First page
- 16838
- Volume
- 6
- Issue
- 20
- ISSN
- 2046-2069
- Open access status
- Out of scope for open access requirements
- Month of publication
- February
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
3
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This work presents research funded by the Newton Fund to support an international collaboration (NCRP/1415) on the fabrication of a novel injectable hyaluronic acid hydrogel (HAG) scaffold, cross-linked with 1,4-butanediol diglycidyl ether (BDDE). This study demonstrates that the new HAG material has similar viscoelastic and water absorbing properties to biological tissues (e.g. epidermis, dermis) and confirms its feasibility as an injectable scaffold to regenerate cartilage and dentin-pulp complex in nude mice. This work promoted further collaboration with the same (East China University of Science and Technology) and new (Shanghai Jiao Tong University) partners and resulted in an additional publication (https://doi.org/10.1016/j.cej.2020.124649).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -