Two-photon fluorescence imaging with 30 fs laser system tunable around 1 micron
- Submitting institution
-
University of Sussex
- Unit of assessment
- 12 - Engineering
- Output identifier
- 439645_72329
- Type
- D - Journal article
- DOI
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10.1364/OE.22.016456
- Title of journal
- Optics Express
- Article number
- -
- First page
- 16456
- Volume
- 22
- Issue
- 13
- ISSN
- 1094-4087
- Open access status
- Out of scope for open access requirements
- Month of publication
- -
- Year of publication
- 2014
- URL
-
http://dx.doi.org/10.1364/OE.22.016456
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
8
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Ultrafast Ti:sapphire laser sources have been used in nonlinear microscopy given its large peak powers and its broad tunability range. However, its complexity, and high cost have limited the widespread adoption of these technology into imaging techniques for daily routine biomedical applications. This is significant because by using a solid-state Yb-tungstate laser allows solving the pricing problem of Ti:Sapphire laser technologies by using spectral broadening via a microstructured fibre followed by pulse compression for having the necessary peak powers, making it suitable for its use for non-linear microscopy. This technology is commercialized by Time bandwidth products now part of Lumentum.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -