Binding of Filamentous Actin to CaMKII as a Potential Mechanism for the Regulation of Bidirectional Synaptic Plasticity by betaCaMKII in Cerebellar Purkinje Cells
- Submitting institution
-
University of Hertfordshire
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 20233661
- Type
- D - Journal article
- DOI
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10.1038/s41598-020-65870-9
- Title of journal
- Scientific Reports
- Article number
- 9019
- First page
- -
- Volume
- 10
- Issue
- 1
- ISSN
- 2045-2322
- Open access status
- Compliant
- Month of publication
- June
- Year of publication
- 2020
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
3
- Research group(s)
-
-
- Citation count
- 1
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- The article results from an ongoing collaboration with Prof Roque at the University of Sao Paulo, Brazil. It describes a novel computational model of intracellular signalling. Computer simulations of the model explain experimental results by our collaborators at Erasmus Medical Center Rotterdam, which were published in Nature Neuroscience, and they suggest further experiments by these collaborators. The work has been presented at two CNS meetings and led to an invited keynote talk at a workshop on multi-scale modelling at the Bernstein Conference on Computational Neuroscience in 2017 (https://www.bernstein-network.de/en/bernstein-conference/past-conferences/2017/satellite-workshops/multiscale-modeling-and-simulation-dura-bernal-lytton).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
