EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation
- Submitting institution
-
University of Sussex
- Unit of assessment
- 5 - Biological Sciences
- Output identifier
- 158766_72341
- Type
- D - Journal article
- DOI
-
10.1038/s41556-017-0016-9
- Title of journal
- Nature Cell Biology
- Article number
- -
- First page
- 162
- Volume
- 20
- Issue
- -
- ISSN
- 1465-7392
- Open access status
- Compliant
- Month of publication
- January
- Year of publication
- 2018
- URL
-
http://dx.doi.org/10.1038/s41556-017-0016-9
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
18
- Research group(s)
-
-
- Citation count
- 12
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
-
- Author contribution statement
- Prof. Doherty’s group performed all of the comprehensive biochemical studies that characterised the enzyme activities of this novel mitochondrial protein.
These studies were pivotal in identifying its molecular roles in processing RNA intermediates and directing the cellular studies by the Stracker group.
Their contributions were also critical for the final acceptance of this study for publication as they clarified a number of key concerns of the referees.
In addition, the Doherty group also performed 2D gel electrophoresis analysis of replication intermediates that is also included in this study.
- Non-English
- No
- English abstract
- -