Conformational coupling by trans-phosphorylation in calcium-calmodulin-dependent kinase II
- Submitting institution
-
Brunel University London
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 070-203700-20659
- Type
- D - Journal article
- DOI
-
10.1371/journal.pcbi.1006796
- Title of journal
- Plos Computational Biology
- Article number
- e1006796
- First page
- -
- Volume
- 15
- Issue
- 5
- ISSN
- 1553-734X
- Open access status
- Compliant
- Month of publication
- May
- Year of publication
- 2019
- URL
-
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006796
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
2
- Research group(s)
-
1 - Artificial Intelligence (AI)
- Citation count
- 1
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Published in a journal ranked 10% among those in Mathematical and Computational Biology, this paper describes a molecular simulation study on the mechanism of activation of a protein relevant for learning and memory in humans. The impact of the study is a new understanding of allosteric regulation of CaMKII and has led to new hypotheses for drug design.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
